{"id":672,"date":"2026-10-01T14:45:06","date_gmt":"2026-10-01T14:45:06","guid":{"rendered":"https:\/\/minervainstitute.fi\/?page_id=672"},"modified":"2026-10-08T13:08:28","modified_gmt":"2026-10-08T13:08:28","slug":"avhandlingar-fran-minerva-institutet","status":"publish","type":"page","link":"https:\/\/minervainstitute.fi\/sv\/om-forskningsinstitutet\/avhandlingar-fran-minerva-institutet\/","title":{"rendered":"Avhandlingar fr\u00e5n Minerva Institutet"},"content":{"rendered":"
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Avhandlingar fra\u030an Minerva Institutet<\/h1>\n <\/div>\n <\/div>\n <\/section>\n <\/div>\n \n\n
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\n2025<\/h2>\n

Hannes Frederik Bode: Epigenetics of environmental risk factors for breast cancer in cancer-discordant twin pairs. October 1, 2025.
\nAbel Szkalisity: Computational techniques in lipid metabolic studies. July 7, 2025.<\/p>\n

David Micinski: The actin cytoskeleton and axon initial segment function. March 21, 2025.<\/p>\n

2024<\/h2>\n

Vignesh Srinivasan: Novel roles of the protein deubiquitinase USP14 in proteostasis regulation and cell stress responses. October 11, 2024.<\/p>\n

Juuso Taskinen: The role of endoplasmic reticulum membrane contact sites in human endothelial cells. October 4, 2024.<\/p>\n

Taru Knuutinen: The importance of calcium channels in thyroid cancer. September 27, 2024.<\/p>\n

Michelle Renlund-Vikstr\u00f6m: Cardiovascular health in preadolescent children following in-utero exposure to pre-eclampsia. June 7, 2024.<\/p>\n

Suneeta Narumanchi: Septin7b and let-7c modulate cardiac function and regeneration in zebrafish. June 5, 2024.<\/p>\n

2023<\/h2>\n

Juho Pirhonen: Mechanisms of lipid deposition: Application of novel omics techniques, tissue imaging methods, and their synergistic deployment in lipid research. September 29, 2023.<\/p>\n

Pushpa Khanal: Molecular regulation of the dendritic spine initiation. August 11, 2023.<\/p>\n

Selina M\u00e4kinen: Send in the signals: Studies on the mechanism of insulin resistance in human skeletal muscle. February 4, 2023.<\/p>\n

2022<\/h2>\n

Mari Lahelma: Lifestyle factors and lipid metabolism in non-alcoholic fatty liver disease, the metabolic syndrome, and atherosclerotic cardiovascular disease. December 16, 2022.<\/p>\n

Maria Ahonen Mehmeti: Mechanisms of adipocyte dysfunction in metabolic disease and cancer. December 9, 2022.<\/p>\n

2021<\/h2>\n

Kien Dang: Diagnostic and prognostic role of expressed KRAS and BRAF mutations in MAPK\/ERK-driven cancers. June 21, 2021.<\/p>\n

Annika Koponen: ORP2 – a lipid-binding protein controlling cellular cholesterol transport and signal transduction. April 1, 2021.<\/p>\n

Kecheng Zhou: Crosstalk between sphingolipid metabolism and nutrient signaling: Studies on LAPTM4B. March 4, 2021.<\/p>\n

2020<\/h2>\n

Hanna Ruhanen: Hepatic lipid metabolism in cardiometabolic diseases \u2013 protective and adverse effects of genetic variants. October 13, 2020.<\/p>\n

Dan Pham Duc: Novel roles of p75 neurotrophin receptor in Low-density lipoprotein receptor regulation and lipid signaling. June 4, 2020.<\/p>\n

Veijo Salo: Lipogenic subdomains of the ER: The role of seipin. April 17, 2020.<\/p>\n

Amr Abouelezz: The structure and dynamics of the actin cytoskeleton in the axon initial segment. February 28, 2020.<\/p>\n

2019<\/h2>\n

Iryna Hlushchenko: Actin regulation in dendritic spines: From synaptic plasticity to animal behavior and neurodevelopmental disorders. August 16, 2019.<\/p>\n

2018<\/h2>\n

Panu Luukkonen: Heterogeneity of non-alcoholic fatty liver disease \u2013 Genetic and nutritional modulation of hepatic lipid metabolism. September 7, 2018.<\/p>\n

Henriikka Kentala: ORP2 \u2013 A sterol sensor controlling hepatocellular bioenergetics and actin cytoskeletal functions. August 18, 2018<\/p>\n

Raghavendra Mysore: Novel molecular regulators of adipose tissue metabolism. May 18, 2018.<\/p>\n

Anna Tikka: Characterization of ANGPTL3 deficiency and molecular mechanisms of ANGPTL3 deficiency-induced hypolipodemia. January 19, 2018.<\/p>\n

Susanna Lallukka: Non-alcoholic fatty liver disease: The role of insulin resistance, inflammation and the PNPLA3 I148M variant. January 13, 2018.<\/p>\n

2017<\/h2>\n

Jenni Hyysalo: Prevalence and Genetics of Non-Alcoholic Fatty Liver Disease. December 16, 2017.<\/p>\n

Elina Isokuortti: Non-alcoholic fatty liver disease \u2013 Studies on pathogenesis and diagnosis. October 28, 2017.<\/p>\n

Boris Vassilev: Studies on proteins influencing cancer progression and regulating endocytic lipid trafficking. April 28, 2017.<\/p>\n

2016<\/h2>\n

Johanna M\u00e4kel\u00e4: Neuroprotective effects of PGC-1\u03b1 activators in dopaminergic neurons. May 20, 2016.<\/p>\n

2015<\/h2>\n

Veronica Kalhori: Sphingosine-1-phosphate-evoked invasion of follicular thyroid cancer cells: Evidence for the involvement of HIF-1a, MMP2 and MMP9. September 11, 2015.<\/p>\n

Tho Huu Ho: Development of amplification-based technologies for enrichment of nucleic acids with difficult sequences or low-abundance point mutations. February 13, 2015.<\/p>\n

2014<\/h2>\n

Alise Hyrskyluoto: Endoplasmic reticulum stress, regulation of autophagy and ubiquitin-proteosome system in cellular models of Huntington’s Disease. September 12, 2014.<\/p>\n

Leena Juurinen: Insulin therapy in type 2 diabetes – Initiation, impact on liver fat, role of combination therapy with glitazones or glinides. May 16, 2014.<\/p>\n

Jere Paavola: Aberrant intracellular calcium cycling in the heart – Mechanistic insights into catecholaminergic polymorphic ventricular tachycardia and heart failure. March 28, 2014.<\/p>\n

2013<\/h2>\n

Anders Eriksson-Paloj\u00e4rvi: Neurohumoral responce and pathophysiologic changes during progresson of mitral reurgitation in the Cavalier King Charles spaniel. November 29, 2013.<\/p>\n

Wei Wang: Studies on the transcriptional and enzymatic control of steroid metabolism: Regulation by lysosomal acid lipase, 24-dehydrocholesterol reductace, and amyloid precursor protein. November 28, 2013.<\/p>\n

Raili Koivuniemi: Regulation of neural progenitor cell proliferation and fate by proteolytic pathways and inflammatory signals in the brain. September 6, 2013.<\/p>\n

You Zhou: Oxysterol binding protein homologues: Novel functions in intracellular transport and adipogenesis. January 25, 2013.<\/p>\n

2012<\/h2>\n

Noora Putkonen: Organelle specific mechanism of neuronal cell death. October 26, 2012.<\/p>\n

Terhi Vihervaara: The role of oxysterol binding proteins in macrophages. October 5, 2012.<\/p>\n

Paulina Skrobuk: Glucose and lipid metabolism in human skeletal muscle. September 7, 2012.<\/p>\n

2011<\/h2>\n

Ksenia Sevastianova: Combination antiretroviral therapy-associated lipodystrophy: insights into pathogenesis and treatment. November 25, 2011.<\/p>\n

2010<\/h2>\n

P\u00e4ivi Lakkisto: Heme oxygenase-1 in cardiovascular diseases. December 17, 2010.<\/p>\n

Minna Kairisalo: Oxidative stress and XIAP signalling in neuronal cells. October 15, 2010.<\/p>\n

Sami Reijonen: Endoplasmic reticulum stress and cell death mechanisms in the cell model of Huntington’s disease. October 8, 2010.<\/p>\n

Nina Bergelin: Interactions between sphingosine 1-phosphate and vascular endothelial growth factor signaling in thyroid carcinoma cells. September 17, 2010.<\/p>\n

Tero Viitanen: GABAa reseptor mediated signalling in the brain: inhibition, shunting and excitation. June 23, 2010.<\/p>\n

Janne Makkonen: Adipose tissue inflammation, liver fat and insulin resistance in humans. June 18, 2010.<\/p>\n

2008<\/h2>\n

Anna Kotronen: Liver fat in the metabolic syndrome and type 2 diabetes.<\/p>\n

2007<\/h2>\n

Cia Ramstr\u00f6m: Ceramides and DAG as regulators of potassium channel function.<\/p>\n

2006<\/h2>\n

Tomas Blom: Sphingolipid-mediated regulation of cellular calcium signaling and survival.<\/p>\n

2005<\/h2>\n

Mirja Tiikkainen: Effects of weight loss, rosiglitazone and metformin on liver fat content, insulin resistance and gene expression in adipose tissue\u201d<\/p>\n

2004<\/h2>\n

Marjo Tamminen: Vascular and Platelet Function in Insulin Resistance<\/p>\n

Esa Lepp\u00e4nen: Experimental basis for standardization of blood specimen collection. (started in Minerva but was completed in Jyv\u00e4skyl\u00e4)<\/p>\n

2003<\/h2>\n

Elena Korsheninnikova: Molecular mechanisms of insulin resistance in human skeletal muscle and lipodystrophic adipose tissue. July 4, 2003.<\/p>\n

Robert Bergholm: Effects of weight loss, physical training and anti-inflammatory therapy on endothelial function in vivo.<\/p>\n

Jussi Sutinen: Pathogenesis and treatment of lipodystrophy in HIV-infected patients receiving highly active antiretroviral therapy.<\/p>\n

2002<\/h2>\n

Nina Uhlenius: Angiotensin II and nitric oxide in chronic experimental nephritis.<\/p>\n

2001<\/h2>\n

Jukka Westerbacka: Insulin action on large artery stiffness in normal and insulin resistant subjects.<\/p>\n

Satu Vehkavaara: Identification and treatment of endothelial dysfunction and cardiovascular risk markers in disorders of glucose metabolism and in postmenopausal women.<\/p>\n

2000<\/h2>\n

Beno\u00eet Dugu\u00e9: Variabilit\u00e9 Biologique. Influence des facteurs preanalytiques in vivo (stress physique, stress psychologique, chronobiologie) sur les r\u00e9sultants d\u2019analyses de marqueurs biologiques sanguins et cellulaires.<\/p>\n

1999<\/h2>\n

Markus Sundblom: Neuropeptide FF in human blood and cerebrospinal fluid.<\/p>\n

1998<\/h2>\n

Leena Karhap\u00e4\u00e4: Effects of caffeine and thimerosal on the regulation of intracellular calsium concentration in GH4C1 rat pituitary cells.<\/p>\n

1997<\/h2>\n

Marja-Leena Sirvi\u00f6: Endothelin-1; cardiopulmonal expression, metabolism and regulation of atrial natriuretic peptide release.<\/p>\n

1995<\/h2>\n

Antti Virkam\u00e4ki: Mechanism and causes of abnormal carbohydrate metabolism during experimental and natural infections.<\/p>\n

1994<\/h2>\n

Outi Saijonmaa: Endothelin-1: Plasma levels in cold pressor test and regulation in endothelial cells.<\/p>\n

Karri Helin: Neutral endopeptidase inhibition in experimental heart failure.<\/p>\n

1991<\/h2>\n

Sari Tikanoja: Free thyroid hormones in serum: performance of different assay methodologies in thyroid diseases and non-thyroidal illnesses.<\/p>\n

1989<\/h2>\n

Per-Henrik Groop: The relationship between gastric inhibitory polypeptide (GIP) and beta-cell function in man.<\/p>\n

Tuula Tikkanen: Atrial natriuretic peptide in experimental heart failure.<\/p>\n

Kaj Mets\u00e4rinne: Renin substrate in human plasma and amniotic fluid.<\/p>\n

1987<\/h2>\n

Kid T\u00f6rnquist: 1,25-dihydroxyvitamin D3 and the secretion of thyrotropin and prolactin from the rat pituitary gland.<\/p>\n

Katarina Rosenl\u00f6f: Erythropoietin: receptor and comparison with renin substrate.<\/p>\n

1986<\/h2>\n

Virpi Oksanen: Neurosarcoidosis: A clinical, laboratory and neuroradiological study.<\/p>\n

Jean-Louis Gu\u00e9ant:<\/p>\n

1984<\/h2>\n

Markku M. Nieminen: Renin-Aldosterone axis in man following ingestion of ethanol.<\/p>\n

Christel Lamberg-Allardt: Serum 25-hydroxy-vitamin D concentration and vitamin D intake.<\/p>\n

Terje Forslund: Induction of rat angiotensin converting enzyme by captopril and enalapril.<\/p>\n

1983<\/h2>\n

Ilkka Immonen: Factors affecting human plasma renin substrate concentration with emphasis on estrogens and pregnancy.<\/p>\n

1982<\/h2>\n

Jaakko Linkola: Strain differences in water and electrolyte metabolism between alcohol preferring (AA) and alcohol avoiding (ANA) rats.<\/p>\n

Tom Petterson: Pleural effusions in infectious, neoplastic and connective tissue diseases. A study of cellular and immunological reactions with emphasis on the role of T and B lymphoytes.<\/p>\n

1981<\/h2>\n

Ilkka Kouvonen: Structure of the porcine intestinal intrinsic factor (IF) receptor.<\/p>\n

Ilkka Tikkanen: Hypertensive effect of autoimmune nephritis in DOCA-NaCl-treated and in spontaneously hypertensive rats.<\/p>\n

Georg Borgstr\u00f6m: Clinical implications of chromosome aberrations in hematologic neoplasia.<\/p>\n

1980<\/h2>\n

Carola Gr\u00f6nhagen-Riska: Angiotensin converting enzyme and sarcoidosis.<\/p>\n

Fredrika Pekonen: The interaction of thyrotropin with its receptors.<\/p>\n

1978<\/h2>\n

Thomas T\u00f6tterman: Thyroid-infiltrating immunocompetent cells in human autoimmune thyroid disease.<\/p>\n

George Marcoullis: Soluble and membrane-bound proteins involved in vitamin B12 transport.<\/p>\n

Pertti Soveri: Renin in human pregnancy and during oral contraception.<\/p>\n

1975<\/h2>\n

Gustav W\u00e4gar: Effect of TSH and cyclic adenosine 3\u00b4, 5\u00b4-monophosphate on thyroidal protein synthesis.<\/p>\n

Jim Schr\u00f6der: Passage of blood cells between foetus and mother.<\/p>\n

1974<\/h2>\n

Ariel Gordin: Thyrotrophin in human serum; A methodological and clinical study in diseases of the thyroid gland.<\/p>\n

Ulf-H\u00e5kan Stenman: Studies on cobalophilin. Vitamin B12-binding proteins of R-type.<\/p>\n

Ritva-Kajsa Selander: Kromosomala makromolekylers effekt p\u00e5 vissa akridinderivats absorption och fluorescens.<\/p>\n

1973<\/h2>\n

Aldur Eriksson: Human twinning in and around the \u00c5land Islands.<\/p>\n

1972<\/h2>\n

Jorma M\u00e4enp\u00e4\u00e4: Hypothyroidism and autoimmune thyroiditis in childhood.<\/p>\n

Risto Kala: Venous plasma angiotensin II in man. Diurnal variation and response to various postural stimuli and exercise.<\/p>\n

1971<\/h2>\n

Johan Wennstr\u00f6m: Effect of ionizing radiation on the chromosomes in meiotic and mitotic cells.<\/p>\n

Frej Fyhrquist: Radioimmunoassay of plasma angiotensin II in patients with hypertension, in renal transplant recipients, and in anephric patients.<\/p>\n

1970<\/h2>\n

Johan Edgren: Effect of cysteine on chromosome aberrations induced by radiation of human lymphocytes in vitro.<\/p>\n

1969<\/h2>\n

Teddy Weber: Isolation and characterization of a lymphocyte-stimulating leucoagglutinin from red kidney beans. (Phaseolus vulgaris).<\/p>\n

1968<\/h2>\n

Rolf Nordman: Endemic goitre in Finland in the light of thyroids of newborn in 1962-1965.<\/p>\n

Kristian Liewendahl: Iodochloroxyquinoline and the thyroid gland. Metabolism of iodochloroxyquinoline iodine and its effect on the thyroid iodine metabolism in rats.<\/p>\n

1964<\/h2>\n

Kaj Simons: Vitamin B12 binders in human body fluids and blood cells.<\/p>\n

1962<\/h2>\n

Albert de la Chapelle: Cytogenetical and clinical observations in female gonadal dysgenesis.<\/p>\n\n <\/div>\n <\/section>\n\n <\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":666,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-672","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nAvhandlingar fr\u00e5n Minerva Institutet - Minervainstitutet<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/minervainstitute.fi\/sv\/om-forskningsinstitutet\/avhandlingar-fran-minerva-institutet\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Avhandlingar fr\u00e5n Minerva Institutet - Minervainstitutet\" \/>\n<meta property=\"og:url\" content=\"https:\/\/minervainstitute.fi\/sv\/om-forskningsinstitutet\/avhandlingar-fran-minerva-institutet\/\" \/>\n<meta property=\"og:site_name\" content=\"Minervainstitutet\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-08T13:08:28+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/minervainstitute.fi\\\/sv\\\/om-forskningsinstitutet\\\/avhandlingar-fran-minerva-institutet\\\/\",\"url\":\"https:\\\/\\\/minervainstitute.fi\\\/sv\\\/om-forskningsinstitutet\\\/avhandlingar-fran-minerva-institutet\\\/\",\"name\":\"Avhandlingar fr\u00e5n Minerva Institutet - 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