Our focus is to study cardiovascular diseases presenting in the young as well as early cardiovascular disease progression of diseases commonly observed in adult life.
Our group studies the role of genetics and the environment in epigenetic processes, and how these processes relate to the development of common diseases and complex traits.
The main goal is to study the pathogenesis of fatty liver disease and diabetes in humans with a special focus on the role of hepatic mitochondrial metabolism.
The research group investigates the regulatory regimes that our cells employ to maintain their lipid balance and to integrate their lipid status with other vital functions such as cell signaling.
We aim to learn how major membrane and storage lipids, such as cholesterol and triacylglycerols, move in the intracellular milieu and how their compartmentalization in cells is controlled.
The main interest of the group is to understand the various mechanisms regulating metabolism and insulin sensitivity at whole body level as well as specifically in skeletal muscle.