{"id":760,"date":"2026-10-05T07:12:58","date_gmt":"2026-10-05T07:12:58","guid":{"rendered":"https:\/\/minervainstitute.fi\/?post_type=research-groups&p=760"},"modified":"2026-10-12T14:37:12","modified_gmt":"2026-10-12T14:37:12","slug":"monitekijaisten-ominaisuuksien-epigenomiikka","status":"publish","type":"research-groups","link":"https:\/\/minervainstitute.fi\/fi\/tutkimusryhmat\/monitekijaisten-ominaisuuksien-epigenomiikka\/","title":{"rendered":"Monitekij\u00e4isten ominaisuuksien epigenomiikka"},"content":{"rendered":"
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Ryhm\u00e4njohtaja<\/h3>
\r\nMiina Ollikainen, PhD, Dosentti
\r\nmiina.ollikainen@helsinki.fi
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Ryhm\u00e4nj\u00e4senet<\/h3>
\r\nTianyu Zhu, PhD
\r\nYiyan He, PhD
\r\nAino Heikkinen, FM
\r\nMikaela Hukkanen, FM
\r\nVolter Lukander, MSc
\r\nOuti Rahikkala, MSc
\r\nAnnika Opperbeck, MSc
\r\nCaroline H\u00f6gel-Starck, MSc
\r\nVilja Hellbom, trainee
\r\nMia Urjansson, tutkimushoitaja<\/p>\n <\/div>\n <\/div>\n
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Valikoidut julkaisut<\/h3>\n

Heikkinen A, Uusitalo-Kylm\u00e4l\u00e4 L, Blom I, Helge JW, Gillberg L, Seaborne R, Larsen S, Jacques M, Grolaux R, Aaltonen S, Kaprio J, van der Kolk BW, Heinonen S, Eynon N, Pietil\u00e4inen KH, Kivel\u00e4 R, Pirinen E, Ollikainen M. The divergent effects of nicotinamide riboside and high-intensity exercise training on skeletal muscle epigenetic aging. Aging Cell 2026, accepted for publication<\/span><\/p>\n

Zhu T, Farag\u00f3 T, Bollepalli S, Heikkinen A, Hukkanen M, Raitakari O, \u2026 Ollikainen M. EpiSmokEr2: a robust epigenetic classifier for smoking status inference using Illumina EPIC methylation data. Epigenomics, 1\u201311. https:\/\/doi.org\/10.1080\/17501911.2026.2630841<\/p>\n

Drouard G, Argentieri MA, Heikkinen A, Ollikainen M, Kaprio J. Associations between 40-year trajectories of BMI and proteomic and epigenetic aging clocks: deciphering nonlinearity and interactions. Aging Cell 2026, 25(2), e70397. https:\/\/doi.org\/10.1111\/acel.70397<\/p>\n

Cristofari R, Davis L, Bardon G, Fernandes F, Figueroa ME, Franzenburg S, Gauthier-Clerc M, Grande F, Heidrich R, Hukkanen M, Le Maho Y, Ollikainen M, Paciello E, Rampal P, Stenseth NC, Trucchi E, Zahn S, Le Bohec C, Meyer BS. Lifestyle change accelerates epigenetic ageing in King penguins. Nat Commun 2026 17, 3795. https:\/\/doi.org\/10.1038\/s41467-026-70527-8<\/p>\n

Hukkanen M, Kankaanp\u00e4\u00e4 A, Heikkinen A, Kaprio J, Cristofari R, Ollikainen M. Epigenetic aging and lifespan reflect reproductive history in the Finnish Twin Cohort. Nat Commun 2026 Jan 8;17(1):44. doi: 10.1038\/s41467-025-67798-y<\/p>\n

Kuo C, Liu P, Drouard G, Vuoksimaa E, Kaprio J, Ollikainen M, Chen Z, Pilling LC, Atkins JL, Fortinsky RH, Kuchel GA, Diniz BS. A proteomic signature of healthspan. Proc. Natl. Acad. Sci. U.S.A. 2025 122;23 e2414086122, https:\/\/doi.org\/10.1073\/pnas.2414086122<\/p>\n

Drouard G, Suhonen S, Heikkinen A, Wang Z, Kaprio J, Ollikainen M. Multi-Omic Associations of Epigenetic Age Acceleration Are Heterogeneously Shaped by Genetic and Environmental Influences. Aging Cell 2025 May 5 https:\/\/doi.org\/10.1111\/acel.70088<\/p>\n

Heikkinen A, Esser VFC, Lundgren S, Lee SHT, Hakkarainen A, Lundbom J, Kuula J, Groop P-H, Heinonen S, Pajukanta P, Kaprio J, Pietil\u00e4inen KH, Li S, Ollikainen M. Twin pair analysis uncovers links between DNA methylation, mitochondrial DNA quantity and obesity. Nat Commun 2025 16;4374 https:\/\/doi.org\/10.1038\/s41467-025-59576-7<\/p>\n

Drouard G, Wang Z, Heikkinen A, Foraster M, Julvez J, Kanninen KM, van Kamp I, Pirinen M, Ollikainen M, Kaprio J. Lifestyle differences between co-twins are associated with decreased similarity in their internal and external exposome profiles. Scientific Rep 2024;14:21261 https:\/\/doi.org\/10.1038\/s41598-024-72354-7<\/p>\n

Lundgren S, Kuitunen S, Pietil\u00e4inen K, Hurme M, K\u00e4h\u00f6nen M, Mannist\u00f6 S, Perola M, Lehtim\u00e4ki T, Raitakari O, Kaprio J, Ollikainen M. BMI is positively associated with accelerated epigenetic aging in twin pairs discordant for BMI Journal of Internal Medicine, 2022, June 14 https:\/\/doiorg\/101111\/joim13528<\/a><\/p>\n

Rahoitus<\/h3>\n

Sigrid Jus\u00e9liuksen S\u00e4\u00e4ti\u00f6
\nMedicinska underst\u00f6dsf\u00f6reningen Liv och H\u00e4lsa r.f.
\nMinervas\u00e4\u00e4ti\u00f6
\nHelsingin yliopisto, Doctoral Program in Population Helath and Behavior, Doctoral Education Pilot in Precision Cancer Medicine, and the Research Foundation
\nHiLIFE Joint Postdoc Funds
\nSuomen kulttuurirahasto
\nKymenlaakson rahasto
\nJuho Vainion s\u00e4\u00e4ti\u00f6<\/span><\/p>\n

Seuraa meit\u00e4:<\/h3>\n

ResearchGate: Miina Ollikainen; ORCID: https:\/\/orcid.org\/0000-0003-3661-7400
\n<\/a><\/span><\/p>\n

Tutkimusryhm\u00e4n verkkosivu Helsingin yliopiston sivuilla: https:\/\/www.helsinki.fi\/en\/researchgroups\/epigenetics-of-complex-diseases-traits
\n<\/a><\/span><\/p>\n

LinkedIn: https:\/\/www.linkedin.com\/in\/miina-ollikainen-07571896\/<\/a><\/span><\/p>\n\n <\/div>\n <\/section>\n\n <\/div>\n","protected":false},"template":"","class_list":["post-760","research-groups","type-research-groups","status-publish","hentry"],"acf":[],"yoast_head":"\nMonitekij\u00e4isten ominaisuuksien epigenomiikka - Minerva tutkimuslaitos<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/minervainstitute.fi\/fi\/tutkimusryhmat\/monitekijaisten-ominaisuuksien-epigenomiikka\/\" \/>\n<meta property=\"og:locale\" content=\"fi_FI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Monitekij\u00e4isten ominaisuuksien epigenomiikka - Minerva tutkimuslaitos\" \/>\n<meta property=\"og:url\" content=\"https:\/\/minervainstitute.fi\/fi\/tutkimusryhmat\/monitekijaisten-ominaisuuksien-epigenomiikka\/\" \/>\n<meta property=\"og:site_name\" content=\"Minerva tutkimuslaitos\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-12T14:37:12+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/minervainstitute.fi\\\/fi\\\/tutkimusryhmat\\\/monitekijaisten-ominaisuuksien-epigenomiikka\\\/\",\"url\":\"https:\\\/\\\/minervainstitute.fi\\\/fi\\\/tutkimusryhmat\\\/monitekijaisten-ominaisuuksien-epigenomiikka\\\/\",\"name\":\"Monitekij\u00e4isten ominaisuuksien epigenomiikka - 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