{"id":685,"date":"2026-10-05T07:29:36","date_gmt":"2026-10-05T07:29:36","guid":{"rendered":"https:\/\/minervainstitute.fi\/?post_type=research-groups&p=685"},"modified":"2026-10-12T14:36:01","modified_gmt":"2026-10-12T14:36:01","slug":"assosioitu-ryhma-neuronaalinen-signalointi","status":"publish","type":"research-groups","link":"https:\/\/minervainstitute.fi\/fi\/tutkimusryhmat\/assosioitu-ryhma-neuronaalinen-signalointi\/","title":{"rendered":"Assosioitu ryhm\u00e4: Neuronaalinen signalointi"},"content":{"rendered":"
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Ryhm\u00e4njohtaja<\/h3>
\r\nDan Lindholm, LT, professori
\r\ndan.lindholm@helsinki.fi
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Ryhm\u00e4nj\u00e4senet<\/h3>
\r\nOve Eriksson, PhD, Docent
\r\nMuhammad Yasir Asghr, PhD
\r\nChiara Scudari, MSc
\r\nNisa Pitafi, MSc
\r\nAnni M\u00e4enp\u00e4\u00e4, BSc
\r\nPyry Aunola, Medical student
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Valikoidut julkaisut<\/h3>\n

Ajoolabady A, Lindholm D, Ren J, Pratic\u00f2 D (2022) ER Stress and UPR in Alzheimer’s Disease: Mechanisms, Pathogenesis, Treatment. Cell Death Dis. 13:706.<\/p>\n

Cascone, A., Lalowski, M., Lindholm, D., & Eriksson, O. (2022). Unveiling the Function of the Mitochondrial Filament-Forming Protein LACTB in Lipid Metabolism and Cancer. Cells, 11<\/i>(10), 1703.<\/p>\n

Do, H. T., Tselykh, T. V., M\u00e4kel\u00e4, J., Ho, T. H., Olkkonen, V. M., Bornhauser, B. C., Korhonen, L., Zelcer, N. & Lindholm, D. (2012) Fibroblast Growth Factor-21 (FGF21) Regulates Low-density Lipoprotein Receptor (LDLR) Levels in Cells via the E3-ubiquitin Ligase Mylip\/Idol and the Canopy2 (Cnpy2)\/Mylip-interacting Saposin-like Protein (Msap). J Biol Chem. 287, 12602-12611<\/p>\n

Hyrskyluoto A, Bruelle C, Lundh SH, Do HT, Kivinen J, Rappou E, Reijonen S, Waltimo T, Peters\u00e9n \u00c5, Lindholm D, Korhonen L. (2014) Ubiquitin specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1a. Hum Mol Genetics 23, 5928-5939.<\/p>\n

Korhonen L, Paul ER, Karin W\u00e5hl\u00e9n K, Haring L, Vasar E, Vaheri A, Lindholm D. (2023) Multivariate analyses of immune markers reveal increases in plasma EN-RAGE in first-episode psychosis patients. Translational Psychiatry, 13(1):326.doi 10.1038\/s41398-023-02627-8<\/p>\n

Lindholm D, Korhonen L, Eriksson O, and K\u00f5ks S (2017) Recent Insights into the Role of Unfolded Protein Response in ER stress in Health and Disease. Frontiers in Cell and Dev. Biol., 5:48.<\/p>\n

Pham DD, Bruelle C, Thi Do H, Pajanoja C, Jin C, Srinivasan V, Olkkonen VM, Eriksson O, Jauhiainen M, Lalowski M, Lindholm D. (2019) Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells. Cell Death Dis. 11;10(7):537.<\/p>\n

Srinivasan V, Bruelle C, Scifo E, Pham DD, Soliymani R, Lalowski M, Lindholm D. (2020) Dynamic interaction of USP14 with the chaperone HSC70 mediates crosstalk between the proteasome, ER signaling and autophagy. iScience 23(1):100790.<\/p>\n

Srinivasan V, Asghar MY, Zafar S, T\u00f6rnquist K, Lindholm D. (2023) Proliferation and migration of ML1 follicular thyroid cancer cells are inhibited by IU1 targeting USP14: role of proteasome and autophagy flux. Front Cell Dev Biol. 11: 30 aug2023.<\/p>\n

Stepanova P, Kumar D, Cavonius K, Korpikoski J, Sirjala J, Lindholm D, Voutilainen MH (2023) Beneficial behavioral effects of cerebraldopamine neurotrophic factor (CDNF) infusion in the N171-82Q transgenic model of Huntington\u2019s disease. Scientific Report 13:2953.<\/p>\n

Rahoitus<\/h3>\n

Suomen Tiedeseura
\nMagnus Ehrnroothin s\u00e4\u00e4ti\u00f6
\nFinska L\u00e4kares\u00e4llskapet
\nMedicinska Underst\u00f6dsf\u00f6reningen Liv och H\u00e4lsa r.f.<\/p>\n

Seuraa meit\u00e4:<\/h3>\n

Research gate: https:\/\/www.researchgate.net\/profile\/Dan-Lindholm<\/a><\/p>\n\n <\/div>\n <\/section>\n\n <\/div>\n","protected":false},"template":"","class_list":["post-685","research-groups","type-research-groups","status-publish","hentry"],"acf":[],"yoast_head":"\nAssosioitu ryhm\u00e4: Neuronaalinen signalointi - Minerva tutkimuslaitos<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/minervainstitute.fi\/fi\/tutkimusryhmat\/assosioitu-ryhma-neuronaalinen-signalointi\/\" \/>\n<meta property=\"og:locale\" content=\"fi_FI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Assosioitu ryhm\u00e4: Neuronaalinen signalointi - Minerva tutkimuslaitos\" \/>\n<meta property=\"og:url\" content=\"https:\/\/minervainstitute.fi\/fi\/tutkimusryhmat\/assosioitu-ryhma-neuronaalinen-signalointi\/\" \/>\n<meta property=\"og:site_name\" content=\"Minerva tutkimuslaitos\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-12T14:36:01+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/minervainstitute.fi\\\/fi\\\/tutkimusryhmat\\\/assosioitu-ryhma-neuronaalinen-signalointi\\\/\",\"url\":\"https:\\\/\\\/minervainstitute.fi\\\/fi\\\/tutkimusryhmat\\\/assosioitu-ryhma-neuronaalinen-signalointi\\\/\",\"name\":\"Assosioitu ryhm\u00e4: Neuronaalinen signalointi - 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